That said, it's important to recognize that locking in itself is not bad. It does, in fact, serve an important purpose to ensure that applications properly and orderly consume or produce data. The key challenge is with the original manual implementation of it using APIs like getReader() and releaseLock(). With the arrival of automatic lock and reader management with async iterables, dealing with locks from the users point of view became a lot easier.
This was not the first time that microbiologists experienced problems with agar. A phenomenon called “The Great Plate Count Anomaly” baffled researchers in the early 20th century when they observed that the number of cells seen under a microscope didn’t match the actual number of colonies growing on an agar plate. Investigating this discrepancy, researchers found agar itself to be the culprit: when nutrient broths are heated with agar during boiling, harmful byproducts (hydroperoxide) can form due to the reaction of agar with phosphate minerals contained in the media. Researchers can avoid this by autoclaving agar separately from the nutrient broth, or by reducing the amount of agar used.
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